Gastritis and H. pylori: What It Is, How It’s Treated, and What Really Works

Gastritis and H. pylori: What It Is, How It’s Treated, and What Really Works

When your stomach feels like it’s on fire-burning, bloated, or achy after eating-it’s easy to blame spicy food or stress. But if the discomfort sticks around, it might not be a passing upset. You could be dealing with gastritis, a real condition where the lining of your stomach becomes inflamed. And in most cases, it’s not just stress or diet. It’s a tiny bacterium called Helicobacter pylori-and it’s hiding in plain sight.

What Exactly Is Gastritis?

Gastritis isn’t one single disease. It’s a group of conditions where the stomach’s protective lining gets irritated or damaged. Think of it like a sunburn, but inside your stomach. That lining normally shields your stomach wall from the strong acid and enzymes it uses to digest food. When it breaks down, acid starts eating away at the tissue, causing pain, nausea, and sometimes bleeding.

There are two main types: erosive and nonerosive. Erosive gastritis means there are actual sores or breaks in the lining-you might see blood in your vomit or black, tarry stools. Nonerosive is sneakier. The lining is inflamed, but nothing’s visibly torn. This type often comes with no symptoms at all. About half of people with chronic gastritis don’t even know they have it until something worse happens.

The biggest culprit? Helicobacter pylori. This spiral-shaped bacteria lives in the stomach of nearly half the world’s population. In the UK and US, about 1 in 5 adults carry it. But here’s the twist: most never get sick. Only 10-20% of infected people develop ulcers or gastritis. Why? It depends on the strain, your immune system, and how long you’ve had it.

How Do You Know If It’s H. pylori?

If you’ve had ongoing stomach pain, bloating, or nausea for weeks, your doctor won’t just guess. They’ll test for H. pylori. The gold standard is an endoscopy-where a thin camera goes down your throat to look at your stomach and take tiny tissue samples. If the biopsy shows the bacteria, that’s confirmation.

But not everyone needs a scope. Non-invasive tests work well too. The urea breath test is simple: you drink a special liquid, then blow into a bag. If H. pylori is present, it breaks down the liquid and releases carbon dioxide you can detect. Blood tests can show past exposure, but they can’t tell if the infection is still active. Stool tests look for bacterial proteins and are very accurate.

The key is timing. If you’ve been on acid-reducing meds like omeprazole, those can mask the infection. Your doctor will usually ask you to stop them for a week or two before testing.

How Is H. pylori Treated?

Treating H. pylori isn’t like taking an antibiotic for a sore throat. It’s a three-drug combo, taken for 10 to 14 days. This is called triple therapy: a proton pump inhibitor (PPI) like omeprazole or esomeprazole, plus two antibiotics-usually amoxicillin and clarithromycin.

The goal isn’t just to feel better. It’s to kill the bacteria completely. If even one bug survives, it can come back stronger-and resistant. That’s why adherence matters. Missing doses is one of the top reasons treatment fails.

Success rates? Around 80-90% in places where clarithromycin resistance is low. But in the UK and US, resistance has jumped from 10% in 2000 to over 35% today. That means many first-line treatments now fail. When that happens, doctors switch to quadruple therapy: a PPI, bismuth subsalicylate (like Pepto-Bismol), plus two antibiotics-metronidazole and tetracycline. This works in 85-92% of cases, even when clarithromycin doesn’t.

A newer drug, vonoprazan, has been approved in the US since 2022 and is gaining traction in Europe. It’s not an antibiotic-it’s a potassium-competitive acid blocker. It shuts down stomach acid more completely than PPIs. In trials, it cleared H. pylori in over 90% of patients, even after two failed treatments.

What About Side Effects?

The antibiotics are tough. About 6 in 10 people report nausea, diarrhea, or a metallic taste during treatment. Some can’t finish the course. That’s why doctors often prescribe anti-nausea meds like domperidone alongside the antibiotics. Probiotics-especially Lactobacillus and Saccharomyces boulardii-can help reduce side effects and improve success rates by 10-15%.

PPIs are generally safe short-term, but long-term use (over a year) carries risks: lower magnesium, higher chance of bone fractures, and rebound acid reflux when you stop. That’s why treatment is time-limited. After finishing antibiotics, you usually stop the PPI after 4-8 weeks unless you still have symptoms.

A person taking a urea breath test with bacteria-shaped steam and medical lighting.

What If It’s Not H. pylori?

Not all gastritis comes from bacteria. NSAIDs like ibuprofen or aspirin cause about 25-30% of cases. If you’ve been taking them daily for joint pain or headaches, your stomach lining is under constant attack. Stopping them is the first step. If you can’t stop them, your doctor might switch you to a safer painkiller like paracetamol and give you a PPI for protection.

Autoimmune gastritis is rare-only 0.1% of people have it-but it’s serious. Your immune system attacks the cells that make stomach acid and intrinsic factor (needed for B12 absorption). People with this type often develop pernicious anemia. They need lifelong B12 injections, not antibiotics.

Alcohol, stress, and bile reflux can also trigger gastritis. Heavy drinking (more than 30g a day-about two pints of beer) doubles your risk. Cutting back cuts symptoms by 60% within two weeks.

What Happens If You Don’t Treat It?

Left untreated, chronic gastritis doesn’t just cause discomfort. It can lead to ulcers, bleeding, or even stomach cancer. H. pylori infection increases cancer risk by 6-8 times. But here’s the good news: treating it cuts that risk by half. The World Health Organization classifies H. pylori as a Group 1 carcinogen-same as smoking.

That’s why experts now recommend testing and treating H. pylori in people with a family history of gastric cancer, or those from high-risk areas like Eastern Europe or East Asia. In the UK, testing is usually offered if you have persistent symptoms or a history of ulcers.

What Can You Do at Home?

Medication does the heavy lifting, but lifestyle changes help you heal faster and stay healthy.

  • Stop smoking. It slows healing by 35%.
  • Avoid alcohol. Even moderate intake irritates the lining.
  • Eat smaller meals. Large meals stretch the stomach and increase acid pressure.
  • Limit spicy, acidic, or fried foods. They won’t cause gastritis, but they can make symptoms worse.
  • Manage stress. While stress doesn’t cause gastritis, it can make symptoms feel worse.
There’s no magic diet for gastritis. But many people find relief by avoiding trigger foods-coffee, citrus, chocolate, and carbonated drinks are common offenders.

Three antibiotics exploding to defeat H. pylori as the stomach heals like blooming flowers.

How Long Until You Feel Better?

Symptoms often improve within a few days of starting treatment. Pain and nausea usually ease in 3-7 days. But feeling better doesn’t mean you’re cured. The bacteria might still be there.

You’ll need a follow-up test-usually a breath or stool test-4 weeks after finishing antibiotics. This confirms the infection is gone. If it’s still positive, you’ll need a second-line treatment.

What About Rebound Acid?

Many people stop their PPI after treatment and suddenly feel worse than before. That’s rebound acid hypersecretion. Your stomach overcompensates for the lack of acid suppression. It’s not a relapse-it’s a side effect of stopping too fast.

To avoid it, taper off PPIs slowly. Instead of stopping cold, reduce the dose over 2-4 weeks. Talk to your doctor about a plan. Some people need to stay on a low dose for months.

When Should You Worry?

See a doctor right away if you have:

  • Black, tarry stools (sign of bleeding)
  • Vomiting blood or material that looks like coffee grounds
  • Unexplained weight loss
  • Difficulty swallowing
  • Severe, persistent pain that doesn’t improve
These aren’t normal. They could mean an ulcer, bleeding, or something more serious.

Final Thoughts: Is Treatment Worth It?

Yes. Even if you feel fine, treating H. pylori if you have it reduces your long-term risk of ulcers and cancer. It’s not about feeling better today-it’s about protecting your stomach for the next 20 years.

Most people who complete treatment never have gastritis again. Those who don’t? They’re the ones who end up back in the hospital with bleeding ulcers or worse.

Don’t ignore persistent stomach symptoms. Get tested. Treat it properly. And don’t stop your meds early-even if you feel fine. Your stomach will thank you.

Can gastritis go away on its own?

Sometimes, especially if it’s caused by a short-term trigger like alcohol or NSAIDs, mild gastritis can improve without treatment. But if it’s caused by H. pylori, it won’t go away on its own. The bacteria sticks around for years-sometimes decades-and keeps damaging the stomach lining. Left untreated, it can lead to ulcers, bleeding, or even stomach cancer. Testing and treating H. pylori is the only way to stop the damage for good.

Can you test for H. pylori at home?

Yes, there are FDA-approved stool antigen test kits you can buy online or at pharmacies. These are reliable for detecting active infection. But breath tests and blood tests require a doctor’s order. Home stool tests are useful if you’ve been treated and want to check if the bacteria is gone. But if you’re just starting to have symptoms, see a doctor first. They’ll help you choose the right test and interpret the results correctly.

Is H. pylori contagious?

Yes. H. pylori spreads through contaminated food, water, or close contact with saliva or vomit. It’s more common in crowded living conditions or areas with poor sanitation. In the UK, it’s less common than in developing countries, but it can still spread within families. If one person is infected, other household members may need testing-especially if they have symptoms or a history of ulcers.

Can stress cause gastritis?

Stress doesn’t directly cause H. pylori gastritis, but it can worsen symptoms and slow healing. Severe physical stress-like from major surgery, burns, or trauma-can trigger acute erosive gastritis. Emotional stress doesn’t create the infection, but it can make you more sensitive to stomach pain and increase acid production. Managing stress helps you feel better, but it won’t cure the infection. You still need to test for and treat H. pylori if it’s present.

Do I need to avoid certain foods forever?

No. Once H. pylori is cleared and the lining heals, most people can return to their normal diet. Some may find that spicy, acidic, or fatty foods still bother them-but that’s true for many people without gastritis too. There’s no lifelong restriction unless you have another condition like GERD or a food allergy. Focus on healing first, then reintroduce foods slowly to see what you tolerate.

Can H. pylori come back after treatment?

It’s possible, but rare in developed countries like the UK. Reinfection rates are under 2% per year after successful treatment. Most cases of recurrence are due to incomplete treatment-not new infection. That’s why it’s critical to finish all your antibiotics and get a follow-up test. If you live in a high-risk area or have close contacts with active infection, your doctor might suggest testing everyone in the household.

Comments

Jackie Petersen

Jackie Petersen

So let me get this straight - we’re supposed to believe some government-approved combo of antibiotics is the only way? What about herbal remedies? I’ve seen people cure this with garlic, mastic gum, and a lot of prayer. Big Pharma doesn’t want you to know this.

And why are they pushing vonoprazan so hard? Sounds like a patent extension scheme to me.

I’m not taking antibiotics unless I absolutely have to. My gut’s already a war zone.

Also - who tested this on 1000 people? Where’s the data? I don’t trust studies funded by drug companies.

On December 7, 2025 AT 06:17

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