Renagel (Sevelamer) – What It Is and When to Use It

Renagel, whose generic name is sevelamer, is a phosphate binder. It’s prescribed mainly for people with chronic kidney disease (CKD) who are on dialysis. When kidneys can’t get rid of phosphate properly, blood levels rise and can cause bone and heart problems. Renagel binds the extra phosphate in your gut so it leaves the body in the stool instead of staying in the blood.

How to Take Renagel Correctly

The biggest mistake patients make is mixing Renagel with the wrong foods or medicines. Always take the tablets or powder on an empty stomach – at least one hour before or two hours after meals. If you’re using the powder, dissolve it in at least eight ounces of water, juice, or a low‑phosphate drink. Stir well and drink it right away; don’t let it sit because it can become too thick.

Stick to the dose your doctor prescribes. The usual starting dose is 800 mg three times a day, but many people need more. Your doctor will check your blood phosphate levels every few weeks and adjust the dose. Never double up on a missed dose; just resume your normal schedule.

Side Effects and What to Watch For

Renagel is generally safe, but some folks notice a few side effects. The most common are stomach upset, constipation, and a metallic taste. If you get severe nausea, vomiting, or persistent diarrhea, call your doctor. Rarely, the medication can lower blood calcium, so your doctor may also check calcium levels regularly.

Because Renagel can bind other medicines, take it at least 1 hour before or after other oral drugs. This includes antibiotics, iron supplements, and certain heart medicines. If you’re not sure about a specific drug, ask your pharmacist.

Another practical tip: stay hydrated. Drinking enough fluids helps prevent constipation, a common complaint with phosphate binders. If you struggle with constipation, a gentle fiber supplement or a stool softener can make a big difference.

Renagel doesn’t cure kidney disease, but it does manage a key risk factor – high phosphate. By keeping phosphate in check, you reduce the chance of bone pain, vascular calcification, and other complications.

In short, take Renagel on an empty stomach, follow the exact dosing schedule, watch for interactions, and keep your fluid intake up. With these simple steps, you’ll get the most benefit from the medication while keeping side effects to a minimum.

If you have any doubts about your dose, diet, or other meds, reach out to your healthcare team. They’re there to help you fine‑tune the plan so you can stay as healthy as possible.